The so-called man flu has been a punchline for decades, but according to one expert it may be time to stop taking it lightly. Dr. Kyle Sue, a Canadian doctor whose findings are published in the British Medical Journal, claims that physiological differences between men and women can lead to different responses to colds and viruses.
I do think that the research does point towards men having a weaker immune response when it comes to common viral respiratory infections and the flu, he told The Guardian. This is shown in the fact that they [have] worse symptoms, they last longer, they are more likely to be hospitalized and more likely to die from it.
Sue reviewed several studies involving both animals and humans and found that testosterone could dampen the immune systems response to influenza, while female sex hormones could actually boost it. He also cited surveys that found men can take up to twice as long as women to recover from viral illnesses.
There need to be more studies, higher quality studies that control for other factors between ...