Tuesday, January 26, 2021 02:30 PM

[FULL TEXT] CURRENT INSIGHTS INTO IMMUNOTHERAPY APPROACHES FOR FOOD ALLERGY | ITT - DOVE MEDICAL PRESS

Introduction

Food allergies impact approximately 11% of adults and 8% of children in the United States resulting in significant impairment in quality of life (QOL) for those affected and their families, as well as concern for life-threatening anaphylactic reactions prompting emergency room visits and hospitalizations.1,2 The most common parent-reported food allergies in children are to peanut (2.2%), milk (1.9%), shellfish (1.3%), tree nut (1.2%), and egg (0.9%).2 Furthermore, multiple food allergies were reported by 40% of parents.2 Food allergy continues to be of concern due to the above-mentioned and the fact that the prevalence appears to be increasing prompting the need for further research into prevention and treatment.2

The standard of care for food allergy is avoidance of allergens and the use of epinephrine and antihistamines for treatment of allergic reactions. However, over the past decade, there has been increasing research dedicated to potential immunotherapy options for food allergy that would result in desensitization and a decreased frequency of allergic reactions after accidental ingestions. This review article will discuss current immunotherapy options for food allergy with a look toward future directions that may improve the safety and efficacy of food allergy treatment ...

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