(Reuters Health) - Children and adults who take five commonly prescribed types of antibiotics may be more likely to develop kidney stones than people who dont use these medicines, a recent study suggests.
Researchers examined electronic health records collected from 1994 to 2015 for 25,981 people who developed kidney stones and a control group of 259,797 similar individuals who did not. Using the kidney stone diagnosis as an index date, researchers then looked for prior antibiotic prescriptions in both groups.
Exposure three to 12 months before the index date to any of five antibiotics - sulfas, cephalosporins, fluoroquinolones, nitrofurantoin/methenamine, and broad-spectrum penicillins - was associated with an increased risk of kidney stones.
The risk increase associated with these antibiotics ranged from 27 percent higher odds with broad-spectrum penicillins to more than doubled odds with sulfas.
Without a doubt, antibiotics have saved millions of lives and are needed to prevent death and serious harm from infections; the benefits outweigh the potential harms, said lead study author Dr. Gregory Tasian of the Childrens Hospital of Philadelphia.
These results dont suggest that antibiotics should not be prescribed when indicated, Tasian said by email. However, they do support antibiotic stewardship - the judicious and ...