Ibuprofen is a common over-the-counter drug that helps with pain and inflammation.
However, for men, it could compromise their fertility, a new study suggests.
According to the Proceedings of the National Academy of Sciences, prolonged and heavy use of the drug alters human testicular physiology to produce a state of compensated hypogonadism. In common terms, the mans testicles dont secrete enough testosterone and the ability to produce sperm is impaired.
The study involved 31 men, ages 18 to 35. Some took 1,200 milligrams of ibuprofen commonly known as Advil or Motrin, among others every day in two 600 mg doses over a six-week period, while others received a placebo.
The study shows that ibuprofen use results in selective transcriptional repression of endocrine cells in the human testis, the significance on the PNAS site reads. This repression results in the elevation of the stimulatory pituitary hormones, resulting in a state of compensated hypogonadism, a disorder associated with adverse reproductive and physical health disorders.
Despite the results, a lecturer says casual use of the non-steroidal anti-inflammatory drug (NSAID) by men should be just fine.